Guillain-Barre syndrome is a disorder characterized by the body's immune system attacking its peripheral nervous system. Guillain-Barre syndrome is a rare disease (affecting only 1 or 2 people per 100,000) and the syndrome's cause has not been pinpointed. However, in some cases of Guillain-Barre syndrome may follow a surgery, vaccination or infectious illness.
Patients with Guillain-Barre often experience weakness, numbness or tingling that typically starts in the legs and may progress to involve the upper body, arms and face. In several cases, GBS may result complete muscle paralysis and weaken the ability to breathe. The majority of patients fully recover, but permanent weakness may remain in some.